I’d say it depends on what you do and how much collaboration with other people is involved. I have always used standalone clients, and I’m not a fan anything web browser based (or cloud in general). I started using LibreCalc instead of Excel for my job a few months ago. Now that I got used to it, I love it. It loads faster, has regex out of the box. Excel has already become quite enremovedtified, in my opinion.