Apart from blow up printers, the one scariest thing for me about a slicer is losing settings. You spend hours getting your printer dialed in, specific profiles per material and then…
You update your slicer software and it all goes away. I have now learned Cura does this. And does this a lot. Forum posts abound about it. Friends recommend I switch to Prusa because it happened to them. Unfortunately too late for me to write down my old settings, and they’re apparently not in the ~/.config/cura folder anymore. Nice.
FWIW, prusaslicer can also upload and print. The setting to enable it is a bit hidden though… (it’s in printer settings)
I know it should be able to, I could never get it to work though. It just didn’t want to recognise my printer and refused to connect.